Resolution and resolving power: Difference between revisions

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==IUPAC 2013 Reccommendation==
#REDIRECT [[resolution]]
 
The IUPAC definition of resolution in mass spectrometry expresses this value as m/?m, where m is the mass of the ion of interest and ?m is the peak width (peak width definition) or the spacing between two equal intensity peaks with a valley between them no more than 10 % of their height (10 % valley definition) [http://dx.doi.org/10.1351/goldbook]. Resolving power in mass spectrometry is defined as the ability of an instrument or measurement procedure to distinguish between two peaks at m/z values differing by a small amount and expressed as the peak width in mass units [http://dx.doi.org/10.1351/goldbook]. Mass resolving power is defined separately as m/?m in a manner similar to that given above for mass resolution [http://dx.doi.org/10.1351/goldbook]. These definitions of mass resolving power and resolving power in mass spectrometry are contradictory, the former is expressed as a dimensionless ratio and the latter as a mass. The definitions for resolution in mass spectrometry and resolving power in mass spectrometry come from Todds 1991 recommendations [http://dx.doi.org/10.1351/pac199163101541], and the definition for mass resolving power comes from Beynons 1978 recommendations [J. Beynon. Pure Appl. Chem. 50, 65 (1978)]. Beynons work contains no definition for mass resolution.
 
Alternative definitions for resolution and resolving power in mass spectrometry have been proposed [http://mass-spec.lsu.edu/msterms/index.php/Mass_Spec_Desk_Reference][http://dx.doi.org/10.1002/(SICI)1098-2787(1998)17:1<1::AID-MAS1>3.0.CO;2-K]. It has been suggested that resolution be given by ?m and resolving power by m/?m; however, these definitions are not widely used.
 
The majority of the mass spectrometry community uses resolution as defined by IUPAC. The term resolving power is not widely used as a synonym for resolution. In this document, the IUPAC defini- tion of resolution in mass spectrometry remains in place. The definition of resolving power has been adapted from the current IUPAC definition of mass resolving power.
 
==Books defining resolution and/or resolving power==
 
===Books using resolution is m/?m ===
:
:'''Mass Spectrometry and its Applications to Organic Chemistry'''
:J. H. Beynon
:Elsevier, 1960
 
:'''Mass Spectrometry  Organic Chemical Applications'''
:Klaus Biemann
:McGraw-Hill, 1962
 
:'''Lasers and Mass Spectrometry'''
:By David M. Lubman
:Oxford University Press US, 1990
:ISBN 0195059298
 
:'''Interpretation of Mass Spectra'''
:Fred W. McLafferty, Turecek
:University Science Books, 1993
:Language: English
:ISBN-10: 0935702253
 
:'''Mass Spectrometry: Clinical and Biomedical Applications'''
:By Dominic M. Desiderio
:Springer, 1993
:ISBN 0306442612
 
:'''Practical Organic Mass Spectrometry: A Guide for Chemical and Biochemical Analysis'''
:J. R. Chapman
:Wiley_Default, 1995
:ISBN 047195831X
 
:'''Mass Spectrometry for Chemists and Biochemists'''
:Robert Alexander Walker Johnstone, M. E. Rose
:Cambridge University Press, 1996
:ISBN 0521424976
 
:'''Introduction to Mass Spectrometry'''
:By J. Throck Watson
:Lippincott-Raven, 1997
:ISBN 0397516886
 
:'''Ionization Methods in Organic Mass Spectrometry'''
:By Alison E. Ashcroft, Royal Society of Chemistry (Great Britain)
:Royal Society of Chemistry, 1997
:ISBN 0854045708
 
:'''Accelerator Mass Spectrometry: Ultrasensitive Analysis for Global Science'''
:Claudio Tuniz, John R. Bird, Gregory F. Herzog, David Fink
:CRC Press, 1998
:ISBN 0849345383
 
:'''Mass Spectrometry in Biology & Medicine'''
:By A. L. Burlingame, Steven A. Carr, Michael A. Baldwin
:Humana Press, 1999
:ISBN 0896037991
 
:'''Mass Spectrometry and Genomic Analysis'''
:J. Nicholas Housby
:Springer, 2001
:ISBN 0792371739
 
:'''Mass Spectrometry Basics'''
:Christopher G. Herbert, Robert Alexander Walker Johnstone
:CRC Press, 2002
:ISBN 0849313546
 
:'''Liquid Chromatography Mass Spectrometry: An Introduction Robert E. Ardrey'''
:Wiley, 2003
:ISBN-10: 0471498017
 
:'''Mass Spectrometry: A Textbook'''
:J?rgen H. Gross
:Springer, 2004
:ISBN 3540407391
 
:'''Quadrupole Ion Trap Mass Spectrometry'''
:By Raymond E. March, John F. Todd
:Wiley-IEEE, 2005
:ISBN 0471717975
 
:'''The Expanding Role of Mass Spectrometry in Biotechnology'''
:Gary Siuzdak
:McC Pr, 2006
:ISBN 0974245127
 
:'''Quantitative Applications of Mass Spectrometry'''
:Pietro Traldi, Franco Magno, Irma Lavagnini, Roberta Seraglia
:Wiley, 2006
:ISBN-10: 0470025166
 
:'''Assigning Structures to Ions in Mass Spectrometry'''
:John L. Holmes, Christiane Aubry, Paul M. Mayer
:CRC, 2006
:ISBN-10: 0849319501
 
:'''Mass Spectrometry: Principles and Applications'''
:Edmond de Hoffmann, Vincent Stroobant
:Wiley-Interscience, 2007
:ISBN 047003310X
 
:'''Quantitative Proteomics by Mass Spectrometry (Methods in Molecular Biology)'''
:Salvatore Sechi
:Humana Press, 2007
:ISBN-10: 1588295710
 
:'''Computational Methods for Mass Spectrometry Proteomics'''
:Ingvar Eidhammer, Kristian Flikka, Lennart Martens, Svein-Ole Mikalsen
:Wiley-Interscience, 2008
:ISBN-10: 0470512970
 
===Books that use resolution is ?m ===
 
:'''Mass Spectrometry Desk Reference'''
:David Sparkman
:Global View, 2006
:ISBN-10: 0966081390
 
:'''Introduction to Mass Spectrometry: Instrumentation, Applications, and Strategies for Data Interpretation'''
:J. Throck Watson, O. David Sparkman
:Wiley, 2007
:Language: English
:ISBN-10: 0470516348
 
:'''Fundamentals of Contemporary Mass'''
:Chhabil Dass, 2007
:ISBN-10: 0471682292
 
:'''Proteomics in Practice: A Guide to Successful Experimental Design'''
:Reiner Westermeier, Tom Naven, Hans-Rudolf H??pker
:Wiley, 2008
:ISBN-10: 3527319417

Latest revision as of 15:35, 13 June 2013

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