Electron capture dissociation: Difference between revisions

Latest revision as of 11:32, 19 March 2021

Electron capture dissociation (ECD)
IUPAC RECOMMENDATIONS 2013
Process in which multiply protonated molecules interact with low-energy electrons followed by fragmentation. The capture of an electron by the even-electron cation [M + nH]ⁿ⁺ liberates energy and reduces its charge state, thus producing the corresponding [M + nH]^(n-1)+ odd-electron ion, which readily fragments.
Related Term(s):
Reference(s): R. A. Zubarev, N. L. Kelleher, F. W. McLafferty. J. Am. Chem. Soc. 120, 3265 (1998). (http://dx.doi.org/10.1021/ja973478k )
From Definitions of Terms Relating to Mass Spectrometry (IUPAC Recommendations 2013); DOI: 10.1351/PAC-REC-06-04-06 © IUPAC 2013.
Index of Recommended Terms

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-{{DefName|
+{{Final
-An ion/electron interaction wherein a protonated molecule with multiple-charge (designated, e.g. [M+nH]<sup>n+</sup>) combines with an electron of low translational energy (usually less than 3 eV) to form an ion with odd-electron sites which immediately bring about [[Charge-Mediated Fragmentation|charge-mediated fragmentation]]. Particularly when the protonated molecule is polypeptide, the fragmentation exclusively occurs at the peptide backbone if the polypeptide does not contain cystine residues. This term should be distinguished from '[[electron-induced excitation in organics]] ([[EIEIO]])' which involves excitation of the reactant ion with an electron beam.
+|acronym=(ECD)
+|def=Process in which multiply [[protonated molecule]]s interact with low-energy electrons followed by fragmentation. The capture of an electron by the even-electron cation [M + nH]<sup>n+</sup> liberates energy and reduces its charge state, thus producing the corresponding [M + nH]<sup>(n-1)+</sup> [[odd-electron ion]], which readily fragments.
+|rel=
+|ref= R. A. Zubarev, N. L. Kelleher, F. W. McLafferty. J. Am. Chem. Soc. 120, 3265 (1998). (http://dx.doi.org/10.1021/ja973478k )
 }}
+[[Category:Fragmentation]]
-[[Disc]]
-[[Category:Reactions]]