RSS:Mastadon: Difference between revisions

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Latest revision as of 15:04, 23 August 2025

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[1]

(RSS) (BioRxiv All) Interactions of the LINE-1 encoded ORF1p with proteins and chromatin converge on a role in neuronal physiology: Retrotransposons are emerging as novel regulators of embryonic and brain development. We recently demonstrated that the LINE-1 encoded protein ORF1p is abundantly expressed in adult mouse and human neurons, although its function remains unclear. Here, we characterize the ORF1p interactome in differentiated mouse and… biorxiv.org/content/10.1101/20

2025-09-10 00:05:32
[2]

(RSS) (BioRxiv All) Redox regulation of neuroinflammatory pathways contributes to damage in Alzheimers disease brain: The mechanism(s) whereby redox stress mediates aberrant immune signaling in age-related neurological disorders remains largely unknown. Normally, the innate immune system mounts a robust response to infectious stimuli. However, unintentional activation by host-derived factors, such as aggregated proteins associated with… biorxiv.org/content/10.1101/20

2025-09-09 23:04:32
[3]

(RSS) (BioRxiv All) Characterization of the Lipidome of Neurons in Mouse Brain Nuclei using Imaging Mass Spectrometry: Understanding the molecular composition of the brain at cellular level is essential for deciphering the metabolic alterations associated with brain diseases. Furthermore, the different prevalence of some neurological diseases between males and fe-males highlight the importance of incorporating gender factor in such studies. Here, we… biorxiv.org/content/10.1101/...

2025-09-09 22:39:33
[4]

(RSS) (JASMS) [ASAP] Note: An Integrated Miniature Time-of-Flight Mass Spectrometer System with 3D Printing Assisted Design of Versatile Pocket-Size Laser-Induced Acoustic Desorption Source: Journal of the American Society for Mass SpectrometryDOI: 10.1021/jasms.5c00241 dx.doi.org/10.1021/jasms.5c002 (RSS)

2025-09-09 21:22:33
[5]

(RSS) (Biomed Chrom) Serum Metabolomics of Patients with Hepatic Cystic Echinococcosis: ABSTRACT

Hepatic cystic echinococcosis (HCE), a liver manifestation of hydatid disease, is among the 17 neglected tropical diseases (NTDs) prioritized by the WHO for eradication by 2025. Although imaging and serological tests are currently the main diagnostic approaches for HCE, they have notable limitations in sensitivity and specificity. Here, we… analyticalsciencejournals.onli

2025-09-09 20:11:34
[6]

(RSS) (J Phys Chem A) [ASAP] Conformation of Gas-Phase Crown Ether Complexes with Alkaline-Earth and Transition Metal Ions Studied by Cryogenic Ion Mobility–Mass Spectrometry: The Journal of Physical Chemistry ADOI: 10.1021/acs.jpca.5c04497 dx.doi.org/10.1021/acs.jpca.5c

2025-09-09 18:44:34
[7]

(RSS) (ACS Anal Chem) [ASAP] Single-Cell Membrane Molecular Cartography Enabled by Nanoengineered VUV-LDI Mass Spectrometry Imaging: Analytical ChemistryDOI: 10.1021/acs.analchem.5c03479 dx.doi.org/10.1021/acs.analche

2025-09-09 18:12:12
[8]

(RSS) (ACS Anal Chem) [ASAP] De-MSI: A Deep Learning-Based Data Denoising Method to Enhance Mass Spectrometry Imaging by Leveraging the Chemical Prior Knowledge: Analytical ChemistryDOI: 10.1021/acs.analchem.5c02946 dx.doi.org/10.1021/acs.analche

2025-09-09 17:01:10
[9]

(RSS) (BioRxiv All) Proteomic Signatures of Hepatitis B Virus Mutations Reveal Genotype-Specific Host Responses and Biomarker Candidates: Hepatitis B virus (HBV) remains a global health challenge, with viral genetic heterogeneity and mutation-driven resistance complicating treatment outcomes. While previous genomic and transcriptomic studies have characterized HBV mutations, the proteomic consequences of these variants remain underexplored. In this… biorxiv.org/content/10.1101/2...

2025-09-09 16:09:32
[10]

(RSS) (BioRxiv All) MSI.EAGLE: An Open-Source GUI for Streamlined Mass Spectrometry Imaging Analysis: Mass Spectrometry Imaging (MSI) is an emergent tool for analyzing spatial molecular distributions, yet data complexity often hinders effective analysis. MSI.EAGLE, an open-source R-Shiny application, makes analysis accessible for non-specialists by integrating advanced tools in a user-friendly interface. The workflow leverages tools from the… biorxiv.org/content/10.1101/20

2025-09-09 15:21:02
[11]

(RSS) (RCM) Exploring the Fragmentation of Sodiated Species Involving Covalent‐Bond Cleavages for Metabolite Characterization: ABSTRACT

Rationale

Electrospray (ESI), the most popular desorption/ionization technique used in mass spectrometry-based metabolomics, generates both protonated and deprotonated molecules, as well as adduct ions, sodium being the most frequent monoatomic cation entering their composition. With the… analyticalsciencejournals.onli

2025-09-09 13:03:35
[12]

(RSS) (BioRxiv All) Spatial Metabolomics Reveals the Role of Penicillic Acid in Cheese Rind Microbiome Disruption by a Spoilage Fungus: Microbial interactions in cheese rinds influence community structure, food safety, and product quality. But the chemical mechanisms that mediate microbial interactions in cheeses and other fermented foods are generally not known. Here, we investigate how the spoilage mold Aspergillus westerdijkiae chemically… biorxiv.org/content/10.1101/20

2025-09-09 06:49:35
[13]

RSS Feed: (Analyst) Recent advances and applications of electrochemical mass spectrometry for real-time monitoring of electrochemical reactions: Analyst, 2025, Accepted Manuscript
DOI: 10.1039/D5AN00785B, Critical ReviewXuemeng Zhang, Yiteng Zhang, Baozhen Yuan, Qianhao Min
Real-time monitoring of electrochemical reaction is crucial for advancing energy conversion and storage, electrocatalysis, organic electrosynthesis, and… pubs.rsc.org/en/Content/Articl

2025-09-09 04:20:32
[14]

(RSS) A versatile toolkit for drug metabolism studies with GNPS2: from drug development to clinical monitoring nature.com/articles/s41596-025

2025-09-09 02:15:35
[15]

(RSS) (J An Atom Spec) Single Particle ICP-TOFMS for the detection of micro-scale polystyrene and polyvinyl chloride from artificially aged bulk plastic: J. Anal. At. Spectrom., 2025, Accepted Manuscript
DOI: 10.1039/D5JA00213C, Technical Note Open Access &nbsp This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Raquel Gonzalez de Vega, Maximilian Huber, Isabel S. Jüngling, Natalia Ivleva, David Clases
A… pubs.rsc.org/en/Content/Articl

2025-09-08 22:39:33
[16]

(RSS) (BioRxiv All) TurboID proximity interactome mapping reveals NR2E3 association with AP-1 and retinal developmental complexes: The photoreceptor-specific nuclear receptor NR2E3 is a key transcription factor in the retinal transcriptional network, essential in photoreceptor cell fate and maintenance. Various biallelic loss-of-function variants lead to autosomal recessive inherited retinal disease (IRD), while a single missense variant G56R has… biorxiv.org/content/10.1101/20

2025-09-08 21:22:33
[17]

(RSS) (J Ag Food Chem) [ASAP] Mapping Royal Jelly’s Bioactive Profile by Liquid Chromatography Coupled to Trapped Ion Mobility Spectrometry and High-Resolution Mass Spectrometry: Journal of Agricultural and Food ChemistryDOI: 10.1021/acs.jafc.5c04904 dx.doi.org/10.1021/acs.jafc.5c

2025-09-08 20:11:35
[18]

(RSS) (BioRxiv All) Accumulation of ibuprofen in endemic amphipods of Lake Baikal: Pharmaceutical pollutants, including ibuprofen, are now ubiquitously detected in global aquatic ecosystems, exerting significant negative ecological impacts. Lake Baikal organisms have been documented to accumulate ibuprofen and related contaminants. This study quantified ibuprofen concentrations within Lake Baikal's endemic amphipod fauna using high-performance… biorxiv.org/content/10.1101/20

2025-09-08 18:44:33
[19]

(RSS) (JASMS) [ASAP] Algorithm-Driven Chromatographic Method for Prostaglandin Isomer Identification via Tandem Mass Spectrometry: Journal of the American Society for Mass SpectrometryDOI: 10.1021/jasms.5c00231 dx.doi.org/10.1021/jasms.5c002 (RSS)

2025-09-08 17:02:06
[20]

RSS Feed: (Analyst) Production process defects of MiXi beverage detected by neutral desorption extractive electrospray ionization mass spectrometry: Analyst, 2025, 150,4070-4080
DOI: 10.1039/D5AN00299K, PaperLingling Pan, Manman Qin, Leting Wang, Lu Huang, Huiyu Xing, Ning Wang, Tongtong Yang, Liyun Hu, Rui Su, Huanwen Chen
ND-EESI-MS enables online detection of chemical fingerprints of Mixi beverage. Process defects were traced via… pubs.rsc.org/en/Content/Articl

2025-09-08 16:23:33
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