Electron capture dissociation: Difference between revisions
From Mass Spec Terms
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An ion/electron interaction wherein a protonated molecule with multiple-charge (designated, e.g. [M+nH]<sup>n+</sup>) combines with an electron of low translational energy (usually less than 3 eV) to form an ion with odd-electron sites which immediately bring about [[Charge-Mediated Fragmentation|charge-mediated fragmentation]]. Particularly when the protonated molecule is polypeptide, the fragmentation exclusively occurs at the peptide backbone if the polypeptide does not contain cystine residues. This term should be distinguished from '[[electron-induced excitation in organics]] ([[EIEIO]])' which involves excitation of the reactant ion with an electron beam. | An ion/electron interaction wherein a protonated molecule with multiple-charge (designated, e.g. [M+nH]<sup>n+</sup>) combines with an electron of low translational energy (usually less than 3 eV) to form an ion with odd-electron sites which immediately bring about [[Charge-Mediated Fragmentation|charge-mediated fragmentation]]. Particularly when the protonated molecule is polypeptide, the fragmentation exclusively occurs at the peptide backbone if the polypeptide does not contain cystine residues. This term should be distinguished from '[[electron-induced excitation in organics]] ([[EIEIO]])' which involves excitation of the reactant ion with an electron beam. | ||
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Revision as of 01:02, 3 March 2005
| DRAFT DEFINITION |
| Electron capture dissociation |
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An ion/electron interaction wherein a protonated molecule with multiple-charge (designated, e.g. [M+nH]n+) combines with an electron of low translational energy (usually less than 3 eV) to form an ion with odd-electron sites which immediately bring about charge-mediated fragmentation. Particularly when the protonated molecule is polypeptide, the fragmentation exclusively occurs at the peptide backbone if the polypeptide does not contain cystine residues. This term should be distinguished from 'electron-induced excitation in organics (EIEIO)' which involves excitation of the reactant ion with an electron beam. |
| Considered between 2004 and 2006 but not included in the 2006 PAC submission |
| This is an unofficial draft definition presented for information and comment. |
