Mass spectrometry timeline: Difference between revisions
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== 19th Century == | == Timeline == | ||
=== 19th Century === | |||
:'''1886''' | :'''1886''' | ||
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::[[Wilhelm Wien]] demonstrates that canal rays can be deflected using strong electric and magnetic fields. | ::[[Wilhelm Wien]] demonstrates that canal rays can be deflected using strong electric and magnetic fields. | ||
== 20th Century == | === 20th Century === | ||
:'''1905''' | :'''1905''' | ||
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::[[Wolfgang Paul]] receives the Nobel Prize in Physics "for the development of the ion trap technique" | ::[[Wolfgang Paul]] receives the Nobel Prize in Physics "for the development of the ion trap technique" | ||
== 21st Century == | === 21st Century === | ||
:'''2002''' | :'''2002''' | ||
::[[John Fenn]] and [[Koichi Tanaka]] are awarded one-quarter of the Nobel Prize in chemistry each "for the development of soft desorption ionisation methods ... for mass spectrometric analyses of biological macromolecules." | ::[[John Fenn]] and [[Koichi Tanaka]] are awarded one-quarter of the Nobel Prize in chemistry each "for the development of soft desorption ionisation methods ... for mass spectrometric analyses of biological macromolecules." | ||
=External Links= | ==External Links== | ||
:*[http://www.chm.bris.ac.uk/ms/history.html Bristol History of Mass Spectrometry] | :*[http://www.chm.bris.ac.uk/ms/history.html Bristol History of Mass Spectrometry] | ||
Revision as of 13:43, 26 April 2006
Timeline
19th Century
- 1886
- Eugen Goldstein observes canal rays.
- 1898
- Wilhelm Wien demonstrates that canal rays can be deflected using strong electric and magnetic fields.
20th Century
- 1905
- Joseph John Thomson begins his study of positive rays.
- 1906
- Thomson is awarded the Nobel Prize in Physics "in recognition of the great merits of his theoretical and experimental investigations on the conduction of electricity by gases"
- 1919
- Francis Aston constructs the first velocity focusing mass spectrograph with mass resolving power of 130.
- 1922
- Aston is awarded the Nobel Prize in chemistry "for his discovery, by means of his mass spectrograph, of isotopes, in a large number of non-radioactive elements, and for his enunciation of the whole-number rule."
- 1931
- Ernest O. Lawrence invents the cyclotron.
- 1934
- Josef Mattauch and Richard Herzog develop the double-focusing mass spectrograph.
- 1936
- Arthur J. Dempster develops the spark ionization source.
- 1937
- Aston constructs a mass spectrograph with resolving power of 2000.
- 1939
- Lawrence receives the Nobel Prize in Physics for the cyclotron.
- 1942
- Lawrence develops the Calutron for uranium isotope separation.
- 1946
- William Stephens presents the concept of a time-of-flight mass spectrometer.
- 1956
- Fred McLafferty proposes a hydrogen transfer reaction that will come to be known as the McLafferty rearrangement.
- 1959
- Researchers at Dow Chemical interface a gas chromatograph to a mass spectrometer.
- 1966
- Chemical ionization is developed.
- 1968
- Malcolm Dole develops electrospray ionization.
- 1976
- Ronald MacFarlane and co-workers develop plasma desorption mass spectrometry.
- 1984
- John Fenn and co-workers use electrospray to ionize biomolecules.
- 1985
- Franz Hillenkamp, Michael Karas and co-workers describe and coin the term matrix-assisted laser desorption ionization (MALDI).
- 1987
- Koichi Tanaka uses the ????????????????????????ultra fine metal plus liquid matrix method?????????????????????? to ionize intact proteins.
- 1989
- Wolfgang Paul receives the Nobel Prize in Physics "for the development of the ion trap technique"
21st Century
- 2002
- John Fenn and Koichi Tanaka are awarded one-quarter of the Nobel Prize in chemistry each "for the development of soft desorption ionisation methods ... for mass spectrometric analyses of biological macromolecules."
