Template:Resolution controversy

Resolution and resolving power controversy

QUOTED TEXT FROM IUPAC RECOMMENDATIONS 2013
The IUPAC definition of resolution in mass spectrometry expresses this value as m/Δm, where m is the mass of the ion of interest and Δm is the peak width (peak width definition) or the spacing between two equal intensity peaks with a valley between them no more than 10 % of their height (10 % valley definition) [1]. Resolving power in mass spectrometry is defined as the ability of an instrument or measurement procedure to distinguish between two peaks at m/z values differing by a small amount and expressed as the peak width in mass units [2]. Mass resolving power is defined separately as m/Δm in a manner similar to that given above for mass resolution [3]. These definitions of mass resolving power and resolving power in mass spectrometry are contradictory, the former is expressed as a dimensionless ratio and the latter as a mass. The definitions for resolution in mass spectrometry and resolving power in mass spectrometry come from Todds 1991 recommendations [4], and the definition for mass resolving power comes from Beynons 1978 recommendations [5]. Beynons work contains no definition for mass resolution. Alternative definitions for resolution and resolving power in mass spectrometry have been proposed [6][7]. It has been suggested that resolution be given by Δm and resolving power by m/Δm; however, these definitions are not widely used. The majority of the mass spectrometry community uses resolution as defined by IUPAC. The term resolving power is not widely used as a synonym for resolution. In this document, the IUPAC definition of resolution in mass spectrometry remains in place. The definition of resolving power has been adapted from the current IUPAC definition of mass resolving power.
From Definitions of Terms Relating to Mass Spectrometry (IUPAC Recommendations 2013); DOI: 10.1351/PAC-REC-06-04-06 © IUPAC 2013.

Books defining resolution and/or resolving power

Books using resolution is m/Δm

Mass Spectrometry and its Applications to Organic Chemistry

J. H. Beynon, Elsevier, 1960

p. 51 "The terms 'resolution' and 'resolving power' have been used a great deal in the above discussion. It has been assumed that the doublet is 'resolved' when its constituent ion species are 'separated' and that the difficult of separation or 'resolving power' necessary to separate the adjacent mass peaks is given by M/ΔM."

Mass Spectrometry Organic Chemical Applications

Klaus Biemann, McGraw-Hill, 1962

(p. 13) the term resolution is used in different ways Throughout this book resolution will be considered as M/ΔM

Lasers and Mass Spectrometry

By David M. Lubman, Oxford University Press US, 1990, ISBN 0195059298

Interpretation of Mass Spectra

Fred W. McLafferty, Turecek, University Science Books, 1993, Language: English, ISBN 0935702253

Mass Spectrometry: Clinical and Biomedical Applications

By Dominic M. Desiderio

Springer, 1993

ISBN 0306442612

Practical Organic Mass Spectrometry: A Guide for Chemical and Biochemical Analysis

J. R. Chapman

Wiley_Default, 1995

ISBN 047195831X

Mass Spectrometry for Chemists and Biochemists

Robert Alexander Walker Johnstone, M. E. Rose

Cambridge University Press, 1996

ISBN 0521424976

Introduction to Mass Spectrometry

By J. Throck Watson

Lippincott-Raven, 1997

ISBN 0397516886

Ionization Methods in Organic Mass Spectrometry

By Alison E. Ashcroft, Royal Society of Chemistry (Great Britain)

Royal Society of Chemistry, 1997

ISBN 0854045708

Accelerator Mass Spectrometry: Ultrasensitive Analysis for Global Science

Claudio Tuniz, John R. Bird, Gregory F. Herzog, David Fink

CRC Press, 1998

ISBN 0849345383

Mass Spectrometry in Biology & Medicine

By A. L. Burlingame, Steven A. Carr, Michael A. Baldwin

Humana Press, 1999

ISBN 0896037991

Mass Spectrometry and Genomic Analysis

J. Nicholas Housby

Springer, 2001

ISBN 0792371739

Mass Spectrometry Basics

Christopher G. Herbert, Robert Alexander Walker Johnstone

CRC Press, 2002

ISBN 0849313546

Liquid Chromatography Mass Spectrometry: An Introduction Robert E. Ardrey

Wiley, 2003

ISBN-10: 0471498017

Mass Spectrometry: A Textbook

J?rgen H. Gross

Springer, 2004

ISBN 3540407391

Quadrupole Ion Trap Mass Spectrometry

By Raymond E. March, John F. Todd

Wiley-IEEE, 2005

ISBN 0471717975

The Expanding Role of Mass Spectrometry in Biotechnology

Gary Siuzdak

McC Pr, 2006

ISBN 0974245127

Quantitative Applications of Mass Spectrometry

Pietro Traldi, Franco Magno, Irma Lavagnini, Roberta Seraglia

Wiley, 2006

ISBN-10: 0470025166

Assigning Structures to Ions in Mass Spectrometry

John L. Holmes, Christiane Aubry, Paul M. Mayer

CRC, 2006

ISBN-10: 0849319501

Mass Spectrometry: Principles and Applications

Edmond de Hoffmann, Vincent Stroobant

Wiley-Interscience, 2007

ISBN 047003310X

Quantitative Proteomics by Mass Spectrometry (Methods in Molecular Biology)

Salvatore Sechi

Humana Press, 2007

ISBN-10: 1588295710

Computational Methods for Mass Spectrometry Proteomics

Ingvar Eidhammer, Kristian Flikka, Lennart Martens, Svein-Ole Mikalsen

Wiley-Interscience, 2008

ISBN-10: 0470512970

Books that use resolution is Δm

Mass Spectrometry Desk Reference

David Sparkman

Global View, 2006

ISBN-10: 0966081390

Introduction to Mass Spectrometry: Instrumentation, Applications, and Strategies for Data Interpretation

J. Throck Watson, O. David Sparkman

Wiley, 2007

Language: English

ISBN-10: 0470516348

Fundamentals of Contemporary Mass

Chhabil Dass, 2007

ISBN-10: 0471682292

Proteomics in Practice: A Guide to Successful Experimental Design

Reiner Westermeier, Tom Naven, Hans-Rudolf H??pker

Wiley, 2008

ISBN-10: 3527319417