Middle-down proteomics

From Mass Spec Terms
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DRAFT DEFINITION
Middle-down proteomics
Top-down proteomics applied to a protein that has been cleaved into a few large fragments.
Related Term(s): bottom-up proteomics, middle-up proteomics
Reference(s):

http://dx.doi.org/10.1002/mas.20190

This is an unofficial draft definition presented for information and comment.

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External links

  • http://dx.doi.org/10.1007/s13361-019-02201-x F. Lermyte, Y.O. Tsybin, P.B. OConnor, J.A. Loo, Top or Middle? Up or Down? Toward a Standard Lexicon for Protein Top-Down and Allied Mass Spectrometry Approaches, J Am Soc Mass Spectrom (2019)