Resolution and resolving power
IUPAC 2013 Reccommendation
The IUPAC definition of resolution in mass spectrometry expresses this value as m/?m, where m is the mass of the ion of interest and ?m is the peak width (peak width definition) or the spacing between two equal intensity peaks with a valley between them no more than 10 % of their height (10 % valley definition) [1]. Resolving power in mass spectrometry is defined as the ability of an instrument or measurement procedure to distinguish between two peaks at m/z values differing by a small amount and expressed as the peak width in mass units [2]. Mass resolving power is defined separately as m/?m in a manner similar to that given above for mass resolution [3]. These definitions of mass resolving power and resolving power in mass spectrometry are contradictory, the former is expressed as a dimensionless ratio and the latter as a mass. The definitions for resolution in mass spectrometry and resolving power in mass spectrometry come from Todds 1991 recommendations [4], and the definition for mass resolving power comes from Beynons 1978 recommendations [J. Beynon. Pure Appl. Chem. 50, 65 (1978)]. Beynons work contains no definition for mass resolution.
Alternative definitions for resolution and resolving power in mass spectrometry have been proposed [5]<1::AID-MAS1>3.0.CO;2-K . It has been suggested that resolution be given by ?m and resolving power by m/?m; however, these definitions are not widely used.
The majority of the mass spectrometry community uses resolution as defined by IUPAC. The term resolving power is not widely used as a synonym for resolution. In this document, the IUPAC defini- tion of resolution in mass spectrometry remains in place. The definition of resolving power has been adapted from the current IUPAC definition of mass resolving power.
Books defining resolution and/or resolving power
Books using resolution is m/?m
- Mass Spectrometry and its Applications to Organic Chemistry
- J. H. Beynon
- Elsevier, 1960
- Mass Spectrometry Organic Chemical Applications
- Klaus Biemann
- McGraw-Hill, 1962
- Lasers and Mass Spectrometry
- By David M. Lubman
- Oxford University Press US, 1990
- ISBN 0195059298
- Interpretation of Mass Spectra
- Fred W. McLafferty, Turecek
- University Science Books, 1993
- Language: English
- ISBN-10: 0935702253
- Mass Spectrometry: Clinical and Biomedical Applications
- By Dominic M. Desiderio
- Springer, 1993
- ISBN 0306442612
- Practical Organic Mass Spectrometry: A Guide for Chemical and Biochemical Analysis
- J. R. Chapman
- Wiley_Default, 1995
- ISBN 047195831X
- Mass Spectrometry for Chemists and Biochemists
- Robert Alexander Walker Johnstone, M. E. Rose
- Cambridge University Press, 1996
- ISBN 0521424976
- Introduction to Mass Spectrometry
- By J. Throck Watson
- Lippincott-Raven, 1997
- ISBN 0397516886
- Ionization Methods in Organic Mass Spectrometry
- By Alison E. Ashcroft, Royal Society of Chemistry (Great Britain)
- Royal Society of Chemistry, 1997
- ISBN 0854045708
- Accelerator Mass Spectrometry: Ultrasensitive Analysis for Global Science
- Claudio Tuniz, John R. Bird, Gregory F. Herzog, David Fink
- CRC Press, 1998
- ISBN 0849345383
- Mass Spectrometry in Biology & Medicine
- By A. L. Burlingame, Steven A. Carr, Michael A. Baldwin
- Humana Press, 1999
- ISBN 0896037991
- Mass Spectrometry and Genomic Analysis
- J. Nicholas Housby
- Springer, 2001
- ISBN 0792371739
- Mass Spectrometry Basics
- Christopher G. Herbert, Robert Alexander Walker Johnstone
- CRC Press, 2002
- ISBN 0849313546
- Liquid Chromatography Mass Spectrometry: An Introduction Robert E. Ardrey
- Wiley, 2003
- ISBN-10: 0471498017
- Mass Spectrometry: A Textbook
- J?rgen H. Gross
- Springer, 2004
- ISBN 3540407391
- Quadrupole Ion Trap Mass Spectrometry
- By Raymond E. March, John F. Todd
- Wiley-IEEE, 2005
- ISBN 0471717975
- The Expanding Role of Mass Spectrometry in Biotechnology
- Gary Siuzdak
- McC Pr, 2006
- ISBN 0974245127
- Quantitative Applications of Mass Spectrometry
- Pietro Traldi, Franco Magno, Irma Lavagnini, Roberta Seraglia
- Wiley, 2006
- ISBN-10: 0470025166
- Assigning Structures to Ions in Mass Spectrometry
- John L. Holmes, Christiane Aubry, Paul M. Mayer
- CRC, 2006
- ISBN-10: 0849319501
- Mass Spectrometry: Principles and Applications
- Edmond de Hoffmann, Vincent Stroobant
- Wiley-Interscience, 2007
- ISBN 047003310X
- Quantitative Proteomics by Mass Spectrometry (Methods in Molecular Biology)
- Salvatore Sechi
- Humana Press, 2007
- ISBN-10: 1588295710
- Computational Methods for Mass Spectrometry Proteomics
- Ingvar Eidhammer, Kristian Flikka, Lennart Martens, Svein-Ole Mikalsen
- Wiley-Interscience, 2008
- ISBN-10: 0470512970
Books that use resolution is ?m
- Mass Spectrometry Desk Reference
- David Sparkman
- Global View, 2006
- ISBN-10: 0966081390
- Introduction to Mass Spectrometry: Instrumentation, Applications, and Strategies for Data Interpretation
- J. Throck Watson, O. David Sparkman
- Wiley, 2007
- Language: English
- ISBN-10: 0470516348
- Fundamentals of Contemporary Mass
- Chhabil Dass, 2007
- ISBN-10: 0471682292
- Proteomics in Practice: A Guide to Successful Experimental Design
- Reiner Westermeier, Tom Naven, Hans-Rudolf H??pker
- Wiley, 2008
- ISBN-10: 3527319417
