Shotgun proteomics
From Mass Spec Terms
| IUPAC RECOMMENDATIONS 2013 |
| Shotgun proteomics |
|---|
| Protein identification using a combination of high-performance liquid chromatography and mass spectrometry in which the proteins in a mixture are digested, usually by a specific enzyme, and the resulting peptides are separated by liquid chromatography and identified by tandem mass spectrometry. |
| Related Term(s): bottom-up proteomics |
| Reference(s): |
| From Definitions of Terms Relating to Mass Spectrometry (IUPAC Recommendations 2013); DOI: 10.1351/PAC-REC-06-04-06 © IUPAC 2013. |
