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- Plasma protein profiling predicts cancer in patients with non-specific symptoms
- Detection of cancer is a challenging task, especially since many common diffuse symptoms overlap with non-malignant conditions. In an article in Nature Communications it was shown that plasma protein profiling can be used to identify cancer among patients with non-specific symptoms.
- 2026-01-29 00:00:00
- Lysophagy - Degrading the degradation factories
- The ability to balance the amount of cellular components, remove damaged entities and recycle molecules by controlled degradation is crucial for cellular function and homeostasis. Lysosomes play a central role by acting as a major hub for degrading proteins, polysaccharides and lipids delivered by autophagy and endocytosis. This is mediated by various hydrolases, specifically acting in the acidic environment maintained in the lysosomal lumen. The lysosomal degradation chamber is isolated from...
- 2026-01-22 00:00:00
- Multiplex tissue image of the month - CAPSL in cervix
- In this edition of multiplex image of this month, calcyphosine like (gene: CAPSL) is visualized in ciliated cells of the cervix.
- 2026-01-14 00:00:00
- Reflections on the HPA year 2025
- 2025 was a year of intensified global conflicts, political instability and climate extremes, but also the year when renewable energy became a larger energy source than coal, the first gene therapy for Huntington's disease showed remarkable results, the first malaria treatment for infants was approved by WHO and the green sea turtle bounced back from near extinction. From the HPA perspective it was an interesting and fruitful year from which we will share some of the highlights.
- 2026-01-08 00:00:00
- Multiplex tissue image of the month - INS in pancreas
- Endocrine pancreas is the new addition to the exploration of protein expression with multiplex immunohistochemistry (mIHC/IF). Cell-specific markers, including insulin (gene: INS), are utilized to map the various endocrine cell types.
- 2025-12-31 00:00:00
