Stable isotope labeling of amino acids in cell culture
From Mass Spec Terms
| IUPAC RECOMMENDATIONS 2013 |
| Stable isotope labeling of amino acids in cell culture (SILAC) |
|---|
| Proteomics technique that detects differences in protein abundance between cultured cell samples using stable isotopic labeling achieved with labeled amino acids in one cell culture and unlabeled ones in a separate culture. |
| Related Term(s): |
| Reference(s):
H. Jiang, A. M. English. J. Proteome Res. 1, 345 (2002). (http://dx.doi.org/10.1021/pr025523f ) S. E. Ong, B. Blagoev, I. Kratchmarova, D. B. Kristensen, H. Steen, A. Pandey, M. Mann. Mol. Cell Proteomics 1, 376 (2002). H. Zhu, S. Pan, S. Gu, E. M. Bradbury, X. Chen. Rapid Commun. Mass Spectrom. 16, 2115 (2002). (http://dx.doi.org/10.1002/rcm.831 ) |
| From Definitions of Terms Relating to Mass Spectrometry (IUPAC Recommendations 2013); DOI: 10.1351/PAC-REC-06-04-06 © IUPAC 2013. |
Gallery
